AstraZeneca's (NYSE: AZN ) phase 3 study of the effectiveness and safety of developmental rheumatoid arthritis drug fostamatinib succeeded in meeting two primary endpoints. The OSKIRA-1 trial showed that fostamatinib increased ACR20 response rates in two different patient groups, according to a statement on the matter from the company. (ACR scores are used in measuring changes in rheumatoid arthritis symptoms.)
The drug also proved safe in the study, with patients tolerating fostamatinib about as well as they had in an earlier phase 2 study. Reported side effects were mild, including diarrhea, nausea, and hypertension.
Dr. Briggs W. Morrison, AstraZeneca's chief medical officer and executive vice president of global medicine development, spoke about fostamatinib's success in the statement, saying, "These top-line results provide important information on the efficacy and safety of fostamatinib and demonstrate that the compound has an effect on the signs and symptoms of rheumatoid arthritis."
5 Best Long Term Stocks To Watch Right Now: WisdomTree Europe SmallCap Dividend Fund (DFE)
WisdomTree Europe SmallCap Dividend Fund is a non-diversified fund. It seeks investment results that closely correspond to the price and yield performance, before fees and expenses, of the WisdomTree Europe SmallCap Dividend Index.
The WisdomTree Europe SmallCap Dividend Index is a fundamentally weighted index that measures the performance of the small-capitalization segment of the European dividend-paying market. The Index is comprised of the companies that compose the bottom 25% of the market capitalization of the WisdomTree Europe Dividend Index.
Advisors' Opinion:- [By Matthew McCall]
The European equity rebound continues and within the region the small cap stocks have been quietly performing very well. The WisdomTree Europe Small Cap Dividend ETF (NYSE: DFE) focuses on small cap stocks that pay high dividends.
Best Industrial Disributor Stocks For 2014: Authentidate Holding Corp.(ADAT)
Authentidate Holding Corp. provides secure Web-based software applications and telehealth products and services in the United States. It offers Inscrybe Healthcare, a Web-based health information exchange and workflow automation solution that enables healthcare industry participants to exchange and track a range of documents, certificates, authorizations, and other information over various modes of communication, including electronic and fax delivery; Inscrybe Office, a Web-based service to sign, seal, and confirm receipt of important documents; and AuthentiProof, a content integrity and time-and-date stamp application. The company also provides the in-home ExpressMD solution, which integrates Electronic House Call in-home patient vital signs monitoring system with a software interface based on the Inscrybe Healthcare platform. It serves integrated delivery networks, physician groups and networks, managed care organizations, hospitals, medical centers, home health agencies , pharmacies, governments, and public health organizations through direct sales and reseller arrangements. The company was formerly known as Bitwise Designs, Inc. and changed its name to Authentidate Holding Corp. in March 2001. Authentidate Holding Corp. was founded in 1985 and is based in Berkeley Heights, New Jersey.
Advisors' Opinion:- [By James E. Brumley]
In a perfect world, a stock's price is merely a reflection of a predictable combination of a company's history and forward-looking prospects. We don't live - or trade - in a perfect world though. In the real world, a chart not only tells a story, but illustrates traders' changing opinion of a stock. The good news is, traders move, thing, buy, and sell in fairly predictable patterns, and when you see certain hints fall in place, you can make a very good trade. Enter Authentidate Holding Corp. (NASDAQ:ADAT) and Greenhunter Resources Inc. (NYSEMKT:GRH). Both GRH as well as ADAT have taken on a bullish shape as of today, and both are apt to be at much higher levels in the foreseeable future.
Best Industrial Disributor Stocks For 2014: Hewlett-Packard Company(HPQ)
Hewlett-Packard Company and its subsidiaries provide products, technologies, software, solutions, and services to individual consumers and small- and medium-sized businesses (SMBs), as well as to the government, health, and education sectors worldwide. Its Personal Systems Group segment offers commercial personal computers (PCs), consumer PCs, workstations, calculators and other related accessories, and software and services for the commercial and consumer markets. The company?s Services segment provides consulting, outsourcing, and technology services to infrastructure, applications, and business process domains. Its Imaging and Printing Group segment provides consumer and commercial printer hardware, supplies, media, and scanning devices, such as inkjet and Web solutions, laser jet and enterprise solutions, managed enterprise solutions, graphics solutions, and printer supplies. The company?s Enterprise Servers, Storage, and Networking segment offers industry standard s ervers, business critical systems, storage platforms, and networking products, including switches, routers, wireless LAN, and TippingPoint network security products. Its HP Software segment provides enterprise IT management software, information management solutions, and security intelligence/risk management solutions. The company?s HP Financial Services segment offers leasing, financing, utility programs, and asset recovery services; and financial asset management services for enterprise customers, as well as specialized financial services to SMBs, and educational and governmental entities. Hewlett-Packard Company also provides business intelligence solutions that enable businesses to standardize on consistent data management schemes, connect and share data across the enterprise, and apply analytics, as well as licenses its specific technology to third parties. The company was founded in 1939 and is headquartered in Palo Alto, California.
Advisors' Opinion:- [By Paul Ausick]
Dell Inc. (NASDAQ: DELL) posted its highest-ever share of the global server market — 18.8% — as competitors International Business Machines Corp. (NYSE: IBM) and Hewlett-Packard Co. (NYSE: HPQ) both lost share. That s the good news for Dell; the bad news is that the worldwide market is shrinking.
Best Industrial Disributor Stocks For 2014: Onconova Therapeutics Inc (ONTX)
Onconova Therapeutics, Inc. (Onconova), incorporated on December 22, 1998, is a clinical-stage biopharmaceutical company focused on discovering and developing small molecule drug candidates to treat cancer. The Company has created a targeted anti-cancer agents designed to work against specific cellular pathways, which promote cancer. It has three clinical-stage product candidates and six preclinical programs. Its preclinical pipeline includes six programs, which target kinases, cellular metabolism or division.
Rigosertib
Rigosertib, the Company�� product candidate, is being tested in a range of ongoing Phase-II and Phase-III clinical trials. The Company is conducting a pivotal phase-III trial of rigosertib under a Special Protocol Assessment (SPA), from the United States Food and Drug Administration (FDA), for higher risk myelodysplastic syndromes (MDS). The Company is also evaluating rigosertib in a Phase-III trial for metastatic pancreatic cancer, in two Phase-II trials for transfusion-dependent lower risk MDS, and in a Phase-II trial for head and neck cancers. Rigosertib has been granted orphan drug status for MDS in both the United States and Europe, as well as orphan drug status for pancreatic cancer in the United States. Baxter Healthcare SA (Baxter), a subsidiary of Baxter International Inc., has commercialization rights for rigosertib in Europe and SymBio Pharmaceuticals Limited (SymBio), has commercialization rights in Japan and Korea. Rigosertib is an inhibitor of two cellular signaling pathways: phosphoinositide 3-kinase (PI3K), and polo-like kinase (PLK), both of which are frequently over-active in cancer cells. By inhibiting the PI3K pathway in cancer cells, rigosertib promotes tumor cell apoptosis, or programmed cell death. It is testing both intravenous and oral formulations of rigosertib, referred to as rigosertib IV and rigosertib Oral, in clinical trials.
ON 013105
The Company�� clinical-stage product candidate, ON 013105, is i! n a Phase I trial in patients with relapsed or refractory lymphoma, including an aggressive form of non-Hodgkin's lymphoma identified as mantle cell lymphoma (MCL), and acute lymphoid leukemia (ALL). ON 013105 suppresses the accumulation of cyclin D1 in cancer cells.
Recilisib
The Company�� clinical-stage product candidate, recilisib, is being developed in collaboration with the United States Department of Defense (DoD), for acute radiation syndromes (ARS). The Company has completed four Phase-I trials to evaluate the safety and pharmacokinetics of recilisib in healthy human adult subjects using both subcutaneous and oral formulations, referred to as recilisib SC and recilisib Oral.
Preclinical Programs
The Company�� ON 1231320 is a specific inhibitor of Polo-like Kinase 2 (PLK2), and in preclinical studies, it induced mitotic arrest and reduced tumor burden in mice injected subcutaneously with colon tumor and triple-negative breast cancer cells. The Company�� ON 123300 inhibits the activity of two kinases, cyclin-dependent kinase 4 (CDK4), and AMP-activated protein kinase 5 (ARK5). Its ON 108600 is a dual inhibitor of two growth-regulatory kinases. Cyclin-dependent kinase 9 is over expressed in several cancers, including leukemias and lymphomas. Casein kinase 2 is overexpressed in a range of tumor types. ON 044580 inhibits mutant forms of the two target kinases, including Janus Kinase 2 (JAK2) and imatinib-resistant Bcr-Abl Kinase (Bcr-Abl). Its ON 24 compounds cause tubulin to depolymerize, inducing mitotic arrest in cultured tumor cell lines. Its ON 146040 inhibits the growth of a range of blood cancer cell lines, including Burkitt's lymphoma, MCL, multiple myeloma and chronic myeloid leukemia.
The Company competes with Eisai Inc., Celgene Corporation, Genentech, Inc., Cell Therapeutics, Inc., Cyclacel Pharmaceuticals, Inc., Telik, Inc., Spectrum Pharmaceuticals, Inc., Astex, Array BioPharma Inc., Astellas Pharma, Inc., Threshold! Pharmace! uticals, Inc., Pharmacyclics Inc., Soligenix, Inc., Cellerant Therapeutics, Inc. and Cleveland BioLabs, Inc.
Advisors' Opinion:- [By Roberto Pedone]
Onconova Therapeutics (ONTX), a clinical-stage biopharmaceutical company, focuses on discovering and developing small molecule drug candidates to treat cancer. This stock closed up 2.5% to $5.15 in Thursday's trading session.
Thursday's Range: $4.97-$5.19
52-Week Range: $4.10-$31.13
Thursday's Volume: 132,000
Three-Month Average Volume: 216,102From a technical perspective, ONTX trended modestly higher here with lighter-than-average volume. This stock has been uptrending over the last few weeks, with shares moving higher from its low of $4.10 to its recent high of $5.52. During that uptrend, shares of ONTX have been making mostly higher lows and higher highs, which is bullish technical price action. That move has now pushed shares of ONTX within range of triggering a near-term breakout trade. That trade will hit if ONTX manages to take out Thursday's intraday high of $5.19 to some more key overhead resistance at $5.52 with high volume.
Traders should now look for long-biased trades in ONTX as long as it's trending above some near-term support levels at $4.80 or at $4.50 and then once it sustains a move or close above those breakout levels with volume that hits near or above 216,102 shares. If that breakout gets underway soon, then ONTX will set up to re-test or possibly take out its next major overhead resistance levels at $5.83 to $6.27. Any high-volume move above those levels will then give ONTX a chance to tag $7.
Best Industrial Disributor Stocks For 2014: Boulder Brands Inc (BDBD)
Boulder Brands, Inc., incorporated on May 31, 2005, is a supplier of gluten-free and health and wellness products in the United States and Canada. The Company distributes its products in all retail channels, including natural, grocery, club and mass merchandise. The Company also has a presence in the foodservice and industrial channels. The Company�� product portfolio consists of spreads, milk and other grocery products marketed under the Smart Balance, Earth Balance and Bestlife brands, and gluten-free products sold under the Udi's, Glutino and Gluten-Free Pantry brands. The Company operates in two segments: Smart Balance and Natural. The Smart Balance segment consists of its branded products in spreads, butter, grocery and milk. The Natural segment consists of its Earth Balance, Glutino and Udi's branded products. In December 2013, the Company announced that it has acquired 100% interests of Phil's Fresh Foods, LLC, owner of EVOL Foods (EVOL).
Smart Balance Products
The Smart Balance line of products is available in a range of categories, formats and sizes in the supermarket, mass merchandise and convenience store channels of distribution. Some of the Company�� buttery spreads are also available in bulk and individual serving formats for use in the industrial and foodservice channels. The Company�� Smart Balance buttery spreads are made from a patented blend of natural oils to help balance fats in the consumer's diet and to help improve the good-to-bad cholesterol ratio when used as part of the Smart Balance Food Plan. Smart Balance Spreadable Butters, available in original, light and extra virgin olive oil varieties, are a blend of creamery fresh butter and canola oil that contain less saturated fat than butter, as well as functional ingredients like EPA/DHA Omega-3 and plant sterols.
The Company offers a range of enhanced milk products, with different varieties containing EPA/DHA Omega-3s, plant sterols, and added levels of calcium and protein. The Comp! any use low and fat-free milks enhanced with non-fat milk solids to give the taste and texture of whole or reduced fat milk. The Company�� milk varieties include fat-free milk, 1% lowfat milk and lactose-free milk and are available in markets across the United States. The Company�� peanut butter products contain ALA Omega-3 from flax oil. The Company�� cooking oil and cooking sprays are designed for use in cooking, baking and salads to aid in avoiding trans fat and hydrogenated oils. The Company also markets a Smart Balance Buttery Burst Spray. The spray has zero calories, zero carbs and zero fats per serving and can be used as a pan spray or as a topping.
The Company�� Smart Balance Light Mayonnaise Dressing has half the fat of regular mayonnaise, is non-hydrogenated, contains zero grams of trans fat and contains natural plant sterols and ALA Omega-3. The Company created the Smart Balance Food Plan, incorporating many of its Smart Balance products, in order to help consumers achieve a healthy balance of natural fats in their daily diet. The plan includes menus, as well as numerous recipes.
Natural
The Earth Balance line of products offers a range of buttery spreads, sticks, soymilks, nut butters and vegan mayo dressings formulated for consumers interested in natural, plant based and organic products. Glutino offers a range of shelf stable and frozen gluten-free products, including snack foods, frozen baked goods, frozen entrees and baking mixes, throughout the United States and Canada. Glutino also offers a range of fresh breads under the Genius brand name. Based in Denver, Colorado, Udi's markets gluten-free products under the Udi's Gluten Free Foods brand in the retail market. The Company owns and operates a health and wellness, subscripton-based Website at www.thebestlife.com, which is based on the philosophies of Bob Greene.
The Company competes with Unilever, ConAgra Foods, Dean Foods, Land O' Lakes, Hain Celestial Group, Inc., Food for L! ife, Van'! s, Nature's Path, Mary's Gone Crackers, Enjoy Life, Pamela's Gluten Free, Rudi's Gluten-Free, French Meadow Bakery, Schar, Kinnikinnick, Amy's Gluten Free, Snyder's, Blue Diamond Gluten-Free, Bob's Red Mill Gluten-Free and Food Should Taste Good.
Advisors' Opinion:- [By John Udovich]
However and not helping the stock around that time was a very�lengthy article by the�Prescience Point Research Group on Seeking Alpha entitled: Fleetmatics Group PLC: Accounting Shenanigans Are Inflating Its Financials, While Insiders Sell Aggressively. Investors and shorts alike can read the article and make their own judgment, but some of the commenters have pointed out that similar attack articles from Prescience Point Research Group on stocks like the Active Network Inc (NYSE: ACTV) and Boulder Brands Inc (NASDAQ: BDBD) have backfired on the shorts. With that said, the article does highlight some of the risks investors face with the stock.
- [By Ben Levisohn]
Shares of Hain have gained 2.2% to $79.91 today at 11:13 a.m–and trumping other health-food stocks today.� Annie’s Homegrown (BNNY) has ticked up 0.4% to $49.61, Boulder Brands (BDBD) has risen 0.6% to $15.96 and Whitewave Foods (WWAV) has dropped 1.3% to� $18.93.
- [By WWW.DAILYFINANCE.COM]
sixflags.com Plenty of stocks go up and down in any given week. The gainers inspire us to keep investing. The decliners keep greed in check while reminding us about the risks of the equity markets. Let's go over some of last week's best and worst performers. Regulus Therapeutics (RGLS) -- Up 161 percent last week Last week's biggest winner was a biotech upstart that got welcome news on a potential hepatitis C treatment. Regulus Therapeutics is showing that patients receiving a single injection of its drug are reporting lower viral loads a month later. There are still plenty of regulatory hurdles to clear, but it's certainly encouraging. Select Comfort (SCSS) -- Up 21 percent last week Shares of Select Comfort moved higher after it announced blowout quarterly results. The company behind the Sleep Number air-chambered mattresses saw net sales and earnings per share climb 23 percent and 22 percent, respectively. Select Comfort's strong performance was fueled by an impressive 16 percent spike in comparable-store sales. The favorable momentum is going to linger: Select Comfort is boosting its guidance for the entire year. Six Flags (SIX) -- Up 16 percent last week It was a summer of thrills at Six Flags. Shares of the regional amusement park operator rose like a coaster on a chain lift after it announced better-than-expected revenue growth. Revenue increased 7 percent on a combination of a slight uptick in attendance, higher admission prices, and guests spending more once inside the park. The report was encouraging enough for Six Flags to boost its dividend. The stock is now yielding a hearty 5.3 percent. Boulder Brands (BDBD) -- Down 31 percent last week Shares of Boulder Brands lost nearly a third of their value after the food company behind Smart Balance buttery spreads and EVOL frozen entrees warned of a soft holiday quarter. It now foresees net sales of $132 million to $137 million for the fourth quarter. We would be looking at a sequential dip from
- [By Pendulum]
Gluten-free products are the growth engine for Boulder Brands (BDBD). Certain consumers require gluten-free products for medical reasons, but Boulder Brands believes that the potential for gluten-free products is much wider. Bulls argue that the benefits of gluten-free foods extend to the broader population and consumers will gravitate toward gluten-free over time. Bears argue that only a small segment of the population really requires gluten-free food and the much hyped gluten-free diet (for the broader population) is a fad. In the near term, the company has the potential to benefit from new gluten-free labeling as well as broader distribution and an expanded product offering. With the company trading at a high valuation, after a nice rally, is the optimism about gluten-free already priced-in or is there more upside?
Best Industrial Disributor Stocks For 2014: Indus Motor Company Ltd (INDU)
Indus Motor Company Limited is a Pakistan-based company mainly engaged in the manufacture of automobiles and trucks. The Company is a joint-venture between the House of Habib, Toyota Motor Corporation and Toyota Tsusho Corporation for assembling, progressive manufacturing and marketing of Toyota-branded vehicles in Pakistan. It also acts as the sole distributor of Toyota-branded vehicles in Pakistan. In addition, the Company also acts as the sole distributor of Daihatsu-branded vehicles in Pakistan and has a license for assembling, progressive manufacturing and marketing of these vehicles in Pakistan. Advisors' Opinion:- [By Inyoung Hwang]
The average company in the Russell 2000 gets 84 percent of its sales from the U.S. and is valued at $972 million, compared with 55 percent and $152 billion for the Dow (INDU), data compiled by Bloomberg show.
- [By Lindsey Rupp]
The S&P 500 rose 0.4 percent to 1,568.61 at 4 p.m. in New York. The Dow (INDU) Jones Industrial Average added 59.98 points, or 0.4 percent, to 14,673.46, its highest-ever closing level. About 5.8 billion shares changed hands on U.S. exchanges, 8 percent below the three-month average.
- [By Nikolaj Gammeltoft]
The S&P 500 dropped less than 0.1 percent to 1,691.65, its first weekly decline since June 21. The benchmark index reached a record on July 22 and climbed within 3 points of 1,700 for three straight days before retreating. The Dow Jones Industrial Average (INDU) added 15.09 points, or 0.1 percent, to 15,558.83.
No comments:
Post a Comment